Slc6a8tm1Lbar
Targeted Allele Detail
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Symbol: |
Slc6a8tm1Lbar |
Name: |
solute carrier family 6 (neurotransmitter transporter, creatine), member 8; targeted mutation 1, Laura Baroncelli |
MGI ID: |
MGI:5825017 |
Gene: |
Slc6a8 Location: ChrX:72716756-72726108 bp, + strand Genetic Position: ChrX, 37.38 cM
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Alliance: |
Slc6a8tm1Lbar page
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Allele Type: |
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Targeted (Conditional ready, Null/knockout, Reporter) |
Mutation: |
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Insertion
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Mutation details: This KO first allele (reporter-tagged insertion with conditional potential) was generated using EUCOMM vector (PCS00081_A09). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exons. The critical exons 5 to 7 are thus flanked by loxP sites. For vector details, see Slc6a8tm1a(KOMP)Wtsi.
(J:232606)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Slc6a8 Mutation: |
10 strains or lines available
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ES cells used for allele generation: clone A8, gift fromA. Wutz, Wellcome Trust Centre for Stem Cell Research, Stem Cell Institute, University of Cambridge (J:232606).
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Original: |
J:232606 Baroncelli L, et al., A novel mouse model of creatine transporter deficiency. F1000Res. 2014;3:228 |
All: |
1 reference(s) |
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