Kras^tm1.1Zhng
Targeted Allele Detail

Summary

• Symbol: Kras^tm1.1Zhng
• Name: Kras proto-oncogene, GTPase; targeted mutation 1.1, Jing Zhang
• MGI ID: MGI:5819239
• Synonyms: Kras^2lox, Kras^fl
• Gene: Kras Location: Chr6:145162425-145195965 bp, - strand Genetic Position: Chr6, 77.37 cM, cytoband G2
• Alliance: Kras^tm1.1Zhng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238116
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 1 is flanked with loxP sites. An frt-flanked neomycin selection cassette was removed via Flp-mediated recombination. (J:238116)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kras Mutation: 68 strains or lines available

References

• Original: J:238116 Damnernsawad A, et al., Kras is Required for Adult Hematopoiesis. Stem Cells. 2016 Jul;34(7):1859-71
• All: 6 reference(s)