Cxcr5^tm1.1Bcgen
Targeted Allele Detail

Summary

• Symbol: Cxcr5^tm1.1Bcgen
• Name: C-X-C motif chemokine receptor 5; targeted mutation 1.1, Biocytogen LLC
• MGI ID: MGI:5819096
• Synonyms: CXCR5-GFP knock in
• Gene: Cxcr5 Location: Chr9:44423084-44437741 bp, - strand Genetic Position: Chr9, 24.84 cM
• Alliance: Cxcr5^tm1.1Bcgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236615
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-GFP construct was inserted after the open reading frame. A loxP-flanked Neo cassette was deleted by crossing to cre-deleter mice. (J:236615)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxcr5 Mutation: 25 strains or lines available

References

• Original: J:236615 He R, et al., Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection. Nature. 2016 Aug 02;537(7620):412-428
• All: 2 reference(s)