Tg(Or8a1-OR1A1,-MAPT/mCherry)D736Feins
Transgene Detail

Summary

• Symbol: Tg(Or8a1-OR1A1,-MAPT/mCherry)D736Feins
• Name: transgene insertion D736, Paul Feinstein
• MGI ID: MGI:5819039
• Synonyms: 5*OR1A1Cbeta, 5*OR1A1Cbeta MouSensor, Tg(Olfr151-OR1A1,-MAPT/mCherry)D736Feins
• Transgene: Tg(Or8a1-OR1A1,-MAPT/mCherry)D736Feins Location: unknown
• Alliance: Tg(Or8a1-OR1A1,-MAPT/mCherry)D736Feins page

Transgene origin

• Strain of Origin: CBA x C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Or8a1-OR1A1,-MAPT/mCherry)D736Feins expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  OR1A1 (8383)

  Or1a1	(MGI:3030237)
  Or1a1b	(MGI:1333770)

  contains an IRES-tau-mCherry tag

• Mutation details: The transgene contains 485 bp of the Olfr151 promoter (M71 minigene)and 5 repeats of the 21 bp (5x21) enhancer sequence from the olfactory receptor H-region upstream of the transcriptional start site followed by an IRES-tau-mCherry tagged human OR1A1 gene. This is founder line D736-A8. Eighteen copies of the transgene integrated into this line. Transgene expression is detected in the main olfactory epithelium. (J:238259)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:238259 D'Hulst C, et al., MouSensor: A Versatile Genetic Platform to Create Super Sniffer Mice for Studying Human Odor Coding. Cell Rep. 2016 Jul 26;16(4):1115-25
• All: 1 reference(s)