Obscn^m1Mhda
Chemically induced Allele Detail

Summary

• Symbol: Obscn^m1Mhda
• Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; mutation 1, Martin Hrabe de Angelis
• MGI ID: MGI:5818758
• Synonyms: Obscn^A4269LMhda
• Gene: Obscn Location: Chr11:58885082-59027201 bp, - strand Genetic Position: Chr11, 36.4 cM
• Alliance: Obscn^m1Mhda page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: The molecular lesion is a C-to-A missense mutation (12806C-A) in codon 4269 in exon 47. This is predicted to alter amino acid 4269 from an arginine to a leucine (R4269L) in the encoded protein. (J:237905)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Obscn Mutation: 420 strains or lines available

References

• Original: J:237905 Sabrautzki S, et al., Alleles produced by the Munich ENU mutagenesis project. MGI Direct Data Submission. 2017
• All: 1 reference(s)