Mir335^tm1.1Asf
Targeted Allele Detail

Summary

• Symbol: Mir335^tm1.1Asf
• Name: microRNA 335; targeted mutation 1.1, Atsuko Sehara-Fujisawa
• MGI ID: MGI:5818290
• Synonyms: miR-335^-
• Gene: Mir335 Location: Chr6:30741298-30741395 bp, + strand Genetic Position: Chr6, 12.53 cM
• Alliance: Mir335^tm1.1Asf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237895
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site flanked neomycin resistance gene cassette was inserted into the genome, replacing the target gene, thus creating a null allele. The neo cassette was removed through cre-mediated recombination. (J:237895)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir335 Mutation: 2 strains or lines available

References

• Original: J:237895 Hiramuki Y, et al., Mest but Not MiR-335 Affects Skeletal Muscle Growth and Regeneration. PLoS One. 2015;10(6):e0130436
• All: 1 reference(s)