Il17rc^tm1Koll
Targeted Allele Detail

Summary

• Symbol: Il17rc^tm1Koll
• Name: interleukin 17 receptor C; targeted mutation 1, Jay K Kolls
• MGI ID: MGI:5817797
• Synonyms: Il17rc^fl
• Gene: Il17rc Location: Chr6:113448416-113460124 bp, + strand Genetic Position: Chr6, 52.77 cM, cytoband E3
• Alliance: Il17rc^tm1Koll page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237978
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 4. (J:237978)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il17rc Mutation: 34 strains or lines available

References

• Original: J:237978 Kumar P, et al., Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation. Immunity. 2016 Mar 15;44(3):659-71
• All: 1 reference(s)