Impdh2^tm2.1Bmi
Targeted Allele Detail

Summary

• Symbol: Impdh2^tm2.1Bmi
• Name: inosine monophosphate dehydrogenase 2; targeted mutation 2.1, Beverly S Mitchell
• MGI ID: MGI:5812582
• Synonyms: Impdh2^Del
• Gene: Impdh2 Location: Chr9:108437635-108442776 bp, + strand Genetic Position: Chr9, 59.5 cM
• Alliance: Impdh2^tm2.1Bmi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225937
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Impdh2^tm2Bmi mice were bred to Tg(ACTB-cre)2Mrt/J Actin-Cre mice resulting in pups carrying a germline deletion of the loxP flanked exons 2-9. (J:225937)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Impdh2 Mutation: 39 strains or lines available

References

• Original: J:225937 Lake JI, et al., Neural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeleton. Dev Biol. 2016 Jan 1;409(1):152-165
• All: 1 reference(s)