Rpgrip1^tvrm111
Chemically induced Allele Detail

Summary

• Symbol: Rpgrip1^tvrm111
• Name: retinitis pigmentosa GTPase regulator interacting protein 1; translational research vision model 111
• MGI ID: MGI:5810760
• Gene: Rpgrip1 Location: Chr14:52348161-52401003 bp, + strand Genetic Position: Chr14, 26.81 cM
• Alliance: Rpgrip1^tvrm111 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: This ENU induced c.813+1G>A point transition in a splice acceptor results in the generation of multiple isoforms that lead to premature termination or transcripts with an in-frame deletion of an early exon. (J:243745)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rpgrip1 Mutation: 70 strains or lines available

References

• Original: J:243745 Krebs MP, et al., Mouse models of human ocular disease for translational research. PLoS One. 2017;12(8):e0183837
• All: 2 reference(s)