Efhc2^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Efhc2^em1(IMPC)J
• Name: EF-hand domain (C-terminal) containing 2; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5810347
• Synonyms: Efhc2^em1J
• Gene: Efhc2 Location: ChrX:16998288-17185607 bp, - strand Genetic Position: ChrX, 12.34 cM, cytoband A1.3
• Alliance: Efhc2^em1(IMPC)J page
• IMPC: Efhc2 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences AGAGGATTGTTCCTGTTCTG, ATAAATTCCTGCTAGCCAAA, ATTTGGCTAGCAGGAATTTA, and GGGAGGATCCCAAAAAGTAC that targeted exon(s) ENSMUSE00000443115.2. This resulted in deletion(s) of 17 bp (location: ChrX:17096562-17096578; GRCm39), 379 bp (location: ChrX:17096632-17097010; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Efhc2 Mutation: 10 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)