Gt(ROSA)26Sor^{tm1(CAG-BST2,-EGFP)Bsz}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-BST2,-EGFP)Bsz}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Paul Bieniasz
• MGI ID: MGI:5806877
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-BST2,-EGFP)Bsz} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: CY2.4 (ES Cell)
• Strain of Origin: B6(Cg)-Tyr^c-2J

Mutation description

• Allele Type: Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(CAG-BST2,-EGFP)Bsz} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  BST2 (684)

  Bst2	(MGI:1916800)

• Mutation details: The targeting construct is designed from 5' to 3' as follows: CAG-loxP-neomycin (in reverse transcriptional orientation)-Stop-loxP-human BST2/tetherin cDNA-FRT-IRES-EGFP-FRT-polyA and was introduced to intron 1 of the mouse Gt(ROSA)26Sor locus. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 944 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)