Tmprss6^m5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tmprss6^m5Btlr
• Name: transmembrane serine protease 6; mutation 5, Bruce Beutler
• MGI ID: MGI:5806439
• Synonyms: ekans
• Gene: Tmprss6 Location: Chr15:78323867-78352834 bp, - strand Genetic Position: Chr15, 37.49 cM, cytoband E2
• Alliance: Tmprss6^m5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 78,459,427 (v38) on chromosome 15, or base pair 133,970 in the GenBank genomic region NC_000081 for the gene. The effect of the mutation at the cDNA and protein level have not examined, but the mutation is predicted to result in skipping of the 178-base pair exon 10 (out of 18 total exons), resulting in an in-frame deletion of the 42-base pair exon 6, which encodes amino acid 206-219. (J:236692)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmprss6 Mutation: 44 strains or lines available

References

• Original: J:236692 Reyna C, et al., Mutagenetix entry for ekans. MGI Direct Data Submission. 2016
• All: 1 reference(s)