Tmprss4tm1.2Hum
Targeted Allele Detail
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Symbol: |
Tmprss4tm1.2Hum |
Name: |
transmembrane protease, serine 4; targeted mutation 1.2, Edith Hummler |
MGI ID: |
MGI:5806232 |
Synonyms: |
Tmprss4delta, Tmprss4tm1.1Hum |
Gene: |
Tmprss4 Location: Chr9:45084024-45115390 bp, - strand Genetic Position: Chr9, 24.84 cM
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Alliance: |
Tmprss4tm1.2Hum page
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Germline Transmission: |
Earliest citation of germline transmission:
J:229561
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S5/SvEvBrd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 8. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 9. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 8 and 9. Western blot analysis confirmed the absence of protein expression in the colon.
(J:229561)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tmprss4 Mutation: |
26 strains or lines available
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Original: |
J:229561 Keppner A, et al., Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4. PLoS One. 2015;10(8):e0135224 |
All: |
2 reference(s) |
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