Tfrc^MRI24910
Chemically induced Allele Detail

Summary

• Symbol: Tfrc^MRI24910
• Name: transferrin receptor; MRI24910
• MGI ID: MGI:5806114
• Gene: Tfrc Location: Chr16:32427738-32451612 bp, + strand Genetic Position: Chr16, 23.06 cM
• Alliance: Tfrc^MRI24910 page

Mutation origin

• Strain of Origin: SJL/J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C transition that results in the amino acid substitution of proline for serine at position 161 (S161P). (J:227229)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tfrc Mutation: 63 strains or lines available

References

• Original: J:227229 Lelliott PM, et al., Erythrocytic Iron Deficiency Enhances Susceptibility to Plasmodium chabaudi Infection in Mice Carrying a Missense Mutation in Transferrin Receptor 1. Infect Immun. 2015 Nov;83(11):4322-34
• All: 1 reference(s)