Rtn4^tm1Adlz
Targeted Allele Detail

Summary

• Symbol: Rtn4^tm1Adlz
• Name: reticulon 4; targeted mutation 1, Annarita Di Lorenzo
• MGI ID: MGI:5806072
• Synonyms: Nogo-A/B^f
• Gene: Rtn4 Location: Chr11:29642947-29694331 bp, + strand Genetic Position: Chr11, 16.79 cM
• Alliance: Rtn4^tm1Adlz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228796
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutations: Insertion, Intragenic deletion
• Exons 2 and 3 were floxed. (J:228796)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtn4 Mutation: 130 strains or lines available

References

• Original: J:228796 Cantalupo A, et al., Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure. Nat Med. 2015 Sep;21(9):1028-37
• All: 3 reference(s)