Mir196a-2^tm1.1Cjt
Targeted Allele Detail

Summary

• Symbol: Mir196a-2^tm1.1Cjt
• Name: microRNA 196a-2; targeted mutation 1.1, Clifford J Tabin
• MGI ID: MGI:5805877
• Synonyms: miR-196a2^GFP
• Gene: Mir196a-2 Location: Chr15:102881785-102881869 bp, + strand Genetic Position: Chr15, 58.04 cM
• Alliance: Mir196a-2^tm1.1Cjt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226712
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The microRNA sequence was replaced with an EGFP reporter gene, UTR and floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:226712)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir196a-2 Mutation: 2 strains or lines available

References

• Original: J:226712 Wong SF, et al., Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4884-93
• All: 3 reference(s)