Gt(ROSA)26Sor^{tm1(Aicda)Armr}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Aicda)Armr}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Almudena R Ramiro
• MGI ID: MGI:5805854
• Synonyms: R26AID
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Aicda)Armr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:233982
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Aicda)Armr} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Aicda (MGI:1342279)

• Mutation details: The targeting construct inserted into the locus a floxed STOP cassette, mouse cDNA and GFP reporter gene. (J:233982)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:233982 Perez-Garcia A, et al., AID-expressing epithelium is protected from oncogenic transformation by an NKG2D surveillance pathway. EMBO Mol Med. 2015 Oct;7(10):1327-36
• All: 3 reference(s)