Ackr3^tm1.2Ics
Targeted Allele Detail

Summary

• Symbol: Ackr3^tm1.2Ics
• Name: atypical chemokine receptor 3; targeted mutation 1.2, Mouse Clinical Institute
• MGI ID: MGI:5805282
• Gene: Ackr3 Location: Chr1:90131702-90143446 bp, + strand Genetic Position: Chr1, 45.28 cM
• Alliance: Ackr3^tm1.2Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235634
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was floxed. Flp-mediated recombination removed the neomycin resistance cassette inserted downstream of exon 2. Cre-mediated recombination removed exon 2, which contains the coding sequence. (J:235634)

Expression

In Mice Carrying this Mutation:

60 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ackr3 Mutation: 34 strains or lines available

References

• Original: J:235634 Trousse F, et al., CXCR7 Receptor Controls the Maintenance of Subpial Positioning of Cajal-Retzius Cells. Cereb Cortex. 2015 Oct;25(10):3446-57
• All: 1 reference(s)