Olfm4^tm1Cle
Targeted Allele Detail

Summary

• Symbol: Olfm4^tm1Cle
• Name: olfactomedin 4; targeted mutation 1, Hans Clevers
• MGI ID: MGI:5805249
• Gene: Olfm4 Location: Chr14:80237742-80260581 bp, + strand Genetic Position: Chr14, 42.78 cM
• Alliance: Olfm4^tm1Cle page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232454
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The targeting vector was designed to insert the mCherry-tk fusion protein and neo selection cassette in frame of the ATG in the first exon of the Olfm4 gene. This is a null allele expressing no Olfm4 mRNA shown by in situ hybridization on intestines. The inserted mCherry was not exressed. (J:232454)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Olfm4 Mutation: 32 strains or lines available

References

• Original: J:232454 Schuijers J, et al., Robust cre-mediated recombination in small intestinal stem cells utilizing the olfm4 locus. Stem Cell Reports. 2014 Aug 12;3(2):234-41
• All: 1 reference(s)