Pros1^tm2.1Kame
Targeted Allele Detail

Summary

• Symbol: Pros1^tm2.1Kame
• Name: protein S (alpha); targeted mutation 2.1, Koichi Kokame
• MGI ID: MGI:5804771
• Gene: Pros1 Location: Chr16:62674670-62749709 bp, + strand Genetic Position: Chr16, 36.43 cM
• Alliance: Pros1^tm2.1Kame page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:230086
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exon 3. (J:230086)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pros1 Mutation: 43 strains or lines available

References

• Original: J:230086 Banno F, et al., Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation. Blood. 2015 Nov 5;126(19):2247-53
• All: 1 reference(s)