Etv5^{tm1(cre/ERT2)Brst}
Targeted Allele Detail

Summary

• Symbol: Etv5^{tm1(cre/ERT2)Brst}
• Name: ets variant 5; targeted mutation 1, Barry R Stripp
• MGI ID: MGI:5800318
• Synonyms: Etv5^CreERT2-RFP, Etv5^{tm2(Cre/ERT2,tdTomato)Brst}
• Gene: Etv5 Location: Chr16:22200063-22258320 bp, - strand Genetic Position: Chr16, 13.3 cM, cytoband B1
• Alliance: Etv5^{tm1(cre/ERT2)Brst} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:309489
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 x 129

Mutation description

• Allele Type: Targeted (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Etv5^{tm1(cre/ERT2)Brst} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Etv5 (MGI:1096867)

• Mutation details: The allele contains IRES-cre/ERT2-2A-tdTomato expression cassette followed by frt flanked neo-selection cassette inserted into the 3' UTR of the mouse Etv5 gene generated by homologous recombination in ES cells. (J:309489)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Etv5 (mouse) Summary of all recombinase alleles driven by Etv5. Comparative matrix view of recombinase activities Alliance mouse Etv5 gene page

Expression

In Mice Carrying this Mutation:

31 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Etv5 Mutation: 270 strains or lines available

References

• Original: J:309489 Jones MR, et al., Characterization of Tg(Etv4-GFP) and Etv5 (RFP) Reporter Lines in the Context of Fibroblast Growth Factor 10 Signaling During Mouse Embryonic Lung Development. Front Genet. 2019;10:178
• All: 1 reference(s)