Vsir^tm1.1Itl
Targeted Allele Detail

Summary

• Symbol: Vsir^tm1.1Itl
• Name: V-set immunoregulatory receptor; targeted mutation 1.1, inGenious Targeting Laboratory
• MGI ID: MGI:5796190
• Synonyms: DD1alpha^flox
• Gene: Vsir Location: Chr10:60182630-60208463 bp, + strand Genetic Position: Chr10, 30.26 cM, cytoband B3
• Alliance: Vsir^tm1.1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223648
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT- and loxP-site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exon 2 and 3 floxed. (J:223648)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vsir Mutation: 26 strains or lines available

References

• Original: J:223648 Yoon KW, et al., CELL DEATH. Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53. Science. 2015 Jul 31;349(6247):1261669
• All: 4 reference(s)