Birc7^tm1Gne
Targeted Allele Detail

Summary

• Symbol: Birc7^tm1Gne
• Name: baculoviral IAP repeat-containing 7; targeted mutation 1, Genentech
• MGI ID: MGI:5796180
• Gene: Birc7 Location: Chr2:180570816-180575803 bp, + strand Genetic Position: Chr2, 103.53 cM
• Alliance: Birc7^tm1Gne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191313
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ reporter gene and neomycin resistance cassette replaced the first four exons. Western blot analysis confirmed the absence of protein expression. (J:191313)

Expression

In Mice Carrying this Mutation:

5 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Birc7 Mutation: 15 strains or lines available

References

• Original: J:191313 Varfolomeev E, et al., Characterization of ML-IAP protein stability and physiological role in vivo. Biochem J. 2012 Nov 1;447(3):427-36
• All: 2 reference(s)