Gpr4^tm1Ykam
Targeted Allele Detail

Summary

• Symbol: Gpr4^tm1Ykam
• Name: G protein-coupled receptor 4; targeted mutation 1, Yosuke Kamide
• MGI ID: MGI:5795901
• Gene: Gpr4 Location: Chr7:18946463-18958099 bp, + strand Genetic Position: Chr7, 9.46 cM
• Alliance: Gpr4^tm1Ykam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228833
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A cassette containing the beta-galactosidase/neomycin phosphotransferase fusion gene replaced the coding sequence in exon 2. (J:299020)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr4 Mutation: 26 strains or lines available

References

• Original: J:228833 Kamide Y, et al., Acidic environment augments FcepsilonRI-mediated production of IL-6 and IL-13 in mast cells. Biochem Biophys Res Commun. 2015 Aug 28;464(3):949-55
• All: 2 reference(s)