Saraf^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Saraf^em1(IMPC)J
• Name: store-operated calcium entry-associated regulatory factor; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5795835
• Synonyms: Saraf^em1J
• Gene: Saraf Location: Chr8:34621733-34638001 bp, + strand Genetic Position: Chr8, 20.9 cM, cytoband A3
• Alliance: Saraf^em1(IMPC)J page
• IMPC: Saraf gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences ACCCATGGACCCGCTGAGCA, CGTCAGAGACTAGGTCTACT, CTTCTTAGACTGCTGGCGGG, and GTTAACCTCCTCTTCAAACC that targeted exon(s) ENSMUSE00000210506.4 ENSMUSE00001704860.1 ENSMUSE00001851012.1 ENSMUSE00001851021.1. This resulted in deletion(s) of 4 bp (location: Chr8:34632226-34632229; GRCm39), 501 bp (location: Chr8:34632256-34632756; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Saraf Mutation: 23 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)