Wls^tm1.1Xzg
Targeted Allele Detail

Summary

• Symbol: Wls^tm1.1Xzg
• Name: wntless WNT ligand secretion mediator; targeted mutation 1.1, Xizhi Guo
• MGI ID: MGI:5793037
• Gene: Wls Location: Chr3:159545309-159644300 bp, + strand Genetic Position: Chr3, 82.65 cM
• Alliance: Wls^tm1.1Xzg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:233048
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed the floxed exon 3. (J:233048)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wls Mutation: 36 strains or lines available

References

• Original: J:233048 Cao J, et al., Ablation of Wntless in endosteal niches impairs lymphopoiesis rather than HSCs maintenance. Eur J Immunol. 2015 Sep;45(9):2650-60
• All: 1 reference(s)