Gpr18^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Gpr18^{tm1.1(KOMP)Vlcg}
• Name: G protein-coupled receptor 18; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5792901
• Gene: Gpr18 Location: Chr14:122148846-122153300 bp, - strand Genetic Position: Chr14, 65.86 cM
• Alliance: Gpr18^{tm1.1(KOMP)Vlcg} page
• IMPC: Gpr18 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:233534
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1013bp between positions 122310818-122311830 of Chromosome 14 (Genome Build37). The neomycin selection cassette was removed via Cre-mediated recombination. (J:233534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr18 Mutation: 21 strains or lines available

References

• Original: J:233534 Becker AM, et al., GPR18 Controls Reconstitution of Mouse Small Intestine Intraepithelial Lymphocytes following Bone Marrow Transplantation. PLoS One. 2015;10(7):e0133854
• All: 1 reference(s)