Aldh1b1tm1.1(KOMP)Vlcg
Targeted Allele Detail
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Symbol: |
Aldh1b1tm1.1(KOMP)Vlcg |
Name: |
aldehyde dehydrogenase 1 family, member B1; targeted mutation 1.1, Velocigene |
MGI ID: |
MGI:5792875 |
Synonyms: |
Aldh1b1tm1LacZ |
Gene: |
Aldh1b1 Location: Chr4:45799022-45804604 bp, + strand Genetic Position: Chr4, 24.35 cM, cytoband B2
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Alliance: |
Aldh1b1tm1.1(KOMP)Vlcg page
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IMPC: |
Aldh1b1 gene page |
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Mutant Cell Line: |
11807A-E11 |
Germline Transmission: |
Earliest citation of germline transmission:
J:232360
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Parent Cell Line: |
VGB6 (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Project Collection: |
KOMP-Regeneron
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Intragenic deletion
Vector: ZEN-Ub1
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Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1589bp between positions 45815339-45816927 of Chromosome 4 (Genome Build37). A loxP-flanked PKG-neo selection cassette was removed via Cre-mediated recombination.
(J:232360)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Aldh1b1 Mutation: |
34 strains or lines available
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Original: |
J:232360 Anastasiou V, et al., Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice. Diabetologia. 2016 Jan;59(1):139-50 |
All: |
3 reference(s) |
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