Gnrh1^mpc294H
Chemically induced Allele Detail

Summary

• Symbol: Gnrh1^mpc294H
• Name: gonadotropin releasing hormone 1; muta-ped-c3pde 294, Harwell
• MGI ID: MGI:5792105
• Gene: Gnrh1 Location: Chr14:67982717-67986889 bp, + strand Genetic Position: Chr14, 34.66 cM
• Alliance: Gnrh1^mpc294H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C point mutation that results in the amino acid substitution of proline for serine at position 25 (S25P). (J:234901)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gnrh1 Mutation: 10 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 1 reference(s)