Tg(UBC-Pou5f1,-EGFP)18Dann
Transgene Detail

Summary

• Symbol: Tg(UBC-Pou5f1,-EGFP)18Dann
• Name: transgene insertion 18, Christina Dann
• MGI ID: MGI:5790657
• Synonyms: cOct4
• Transgene: Tg(UBC-Pou5f1,-EGFP)18Dann Location: unknown
• Alliance: Tg(UBC-Pou5f1,-EGFP)18Dann page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(UBC-Pou5f1,-EGFP)18Dann expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pou5f1 (MGI:101893)

• Mutation details: The transgenic construct contains (5' to 3') a human ubiquitin C (UB) gene promoter, a floxed STOP cassette (3 repeats of SV40 polyA stop sequence flanked by loxP sites), the mouse Pou5f1 coding sequence with a myc tag, T2A/furin ribosomal skip sequence, EGFP coding sequence, and a BGH poly(A) sequence. (J:236622)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:236622 Zheng Y, et al., Ectopic POU5F1 in the male germ lineage disrupts differentiation and spermatogenesis in mice. Reproduction. 2016 Oct;152(4):363-77
• All: 1 reference(s)