Abca3^tm1.1Holz
Targeted Allele Detail

Summary

• Symbol: Abca3^tm1.1Holz
• Name: ATP-binding cassette, sub-family A member 3; targeted mutation 1.1, Andreas Holzinger
• MGI ID: MGI:5788724
• Synonyms: ABCA3 neo-
• Gene: Abca3 Location: Chr17:24570997-24629178 bp, + strand Genetic Position: Chr17, 12.38 cM, cytoband A3.3
• Alliance: Abca3^tm1.1Holz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: IDG3.2 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Intragenic deletion
• Mutation details: A 2171-bp SacI/SacII DNA restriction fragment encompassing the 3' end of exon 5 through the 5' end of exon 7 has been replaced by an internal ribosomal entry site (IRES) followed by the coding sequence for humanized Renilla green fluorescent protein and a single loxP site where a loxP-flanked neomycin resistance cassette was excised by Cre recombinase. (J:122736)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abca3 Mutation: 92 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 2 reference(s)