Kdelr1^t-red
Chemically induced Allele Detail

Summary

• Symbol: Kdelr1^t-red
• Name: KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; naive T-cell reduced
• MGI ID: MGI:5788520
• Gene: Kdelr1 Location: Chr7:45522264-45533150 bp, + strand Genetic Position: Chr7, 29.57 cM
• Alliance: Kdelr1^t-red page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C point mutation that results in the amino acid substitution of proline for serine at position 123 (S123P). (J:233546)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdelr1 Mutation: 10 strains or lines available

References

• Original: J:233546 Kamimura D, et al., KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR. Nat Commun. 2015;6:7474
• All: 2 reference(s)