Prdm1^tm4.1Rob
Targeted Allele Detail

Summary

• Symbol: Prdm1^tm4.1Rob
• Name: PR domain containing 1, with ZNF domain; targeted mutation 4.1, Elizabeth J Robertson
• MGI ID: MGI:5788440
• Synonyms: Prdm1^BEG
• Gene: Prdm1 Location: Chr10:44313173-44404497 bp, - strand Genetic Position: Chr10, 23.24 cM
• Alliance: Prdm1^tm4.1Rob page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228771
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting vector inserted at the transcription start site in exon 2 a cDNA of the gene fused with EGFP, SV40 polyadenylation sequence and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:228771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdm1 Mutation: 69 strains or lines available

References

• Original: J:228771 Mould AW, et al., Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation. PLoS Genet. 2015 Jul;11(7):e1005375
• All: 1 reference(s)