Dlat^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dlat^em1(IMPC)J
• Name: dihydrolipoamide S-acetyltransferase; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5788343
• Synonyms: Dlat^em1J
• Gene: Dlat Location: Chr9:50545933-50571080 bp, - strand Genetic Position: Chr9, 27.75 cM
• Alliance: Dlat^em1(IMPC)J page
• IMPC: Dlat gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences CAGCTCAGAACTGACACGTG, CTGAATGCTTTTATGCGTCC, CTTTTTATAAAATATGACCC, and GACCTTGTCACCCATCACAA that targeted exon(s) ENSMUSE00000216202.2. This resulted in deletion(s) of 7 bp (location: Chr9:50564799-50564805; GRCm39), 325 bp (location: Chr9:50564830-50565154; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dlat Mutation: 31 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)