Chrna10^tm1Bjmy
Targeted Allele Detail

Summary

• Symbol: Chrna10^tm1Bjmy
• Name: cholinergic receptor, nicotinic, alpha polypeptide 10; targeted mutation 1, Barbara J Morley
• MGI ID: MGI:5787808
• Synonyms: Chrna10^tm1Geno
• Gene: Chrna10 Location: Chr7:101760473-101766035 bp, - strand Genetic Position: Chr7, 54.71 cM
• Alliance: Chrna10^tm1Bjmy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220194
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exons 1-3. This allele is derived from Chrna10^tm2Geno (J:220194, J:268887)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chrna10 Mutation: 18 strains or lines available

References

• Original: J:220194 Smith ML, et al., Acetylcholine receptors in the retinas of the alpha7 nicotinic acetylcholine receptor knockout mouse. Mol Vis. 2014;20:1328-56
• All: 6 reference(s)