Bcl11a^tm4Peli
Targeted Allele Detail

Summary

• Symbol: Bcl11a^tm4Peli
• Name: BCL11 transcription factor A; targeted mutation 4, Pentao Liu
• MGI ID: MGI:5787806
• Gene: Bcl11a Location: Chr11:24028056-24124123 bp, + strand Genetic Position: Chr11, 14.41 cM
• Alliance: Bcl11a^tm4Peli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219746
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. A floxed neomycin resistance cassette was inserted downstream of exon 1. (J:219746, J:237333)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl11a Mutation: 43 strains or lines available

References

• Original: J:219746 Khaled WT, et al., BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells. Nat Commun. 2015;6:5987
• All: 2 reference(s)