Drc7^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Drc7^em1(IMPC)J
• Name: dynein regulatory complex subunit 7; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5784926
• Synonyms: Drc7^em1J
• Gene: Drc7 Location: Chr8:95781731-95804769 bp, + strand Genetic Position: Chr8, 47.12 cM
• Alliance: Drc7^em1(IMPC)J page
• IMPC: Drc7 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences GCAAGTCTGGGTCTGGGGTA, GCTCAGCAGAGGAGCCGTAG, GCTCTGAGTACAGAGCTGGC, and TCTGACTTCTTGCTCTTCCG that targeted exon(s) ENSMUSE00000502105.3. This resulted in deletion(s) of 292 bp (location: Chr8:95796914-95797205; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Drc7 Mutation: 45 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)