Adgrg1^tm1.1Xhpo
Targeted Allele Detail

Summary

• Symbol: Adgrg1^tm1.1Xhpo
• Name: adhesion G protein-coupled receptor G1; targeted mutation 1.1, Xianhua Piao
• MGI ID: MGI:5784876
• Synonyms: Gpr56^fl
• Gene: Adgrg1 Location: Chr8:95701379-95740845 bp, + strand Genetic Position: Chr8, 47.12 cM
• Alliance: Adgrg1^tm1.1Xhpo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219714
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the selection cassette and left exons 4 through 6 floxed. (J:219714)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgrg1 Mutation: 33 strains or lines available

References

• Original: J:219714 Giera S, et al., The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development. Nat Commun. 2015;6:6121
• All: 6 reference(s)