Erg^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Erg^tm1.1Geno
• Name: ETS transcription factor; targeted mutation 1.1, Genoway
• MGI ID: MGI:5784705
• Synonyms: Erg^fl
• Gene: Erg Location: Chr16:95160028-95387452 bp, - strand Genetic Position: Chr16, 56.04 cM
• Alliance: Erg^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232687
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 6 was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. (J:232687)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Erg Mutation: 28 strains or lines available

References

• Original: J:232687 Birdsey GM, et al., The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/beta-catenin signaling. Dev Cell. 2015 Jan 12;32(1):82-96
• All: 5 reference(s)