Tmie^tm1.1Mull
Targeted Allele Detail

Summary

• Symbol: Tmie^tm1.1Mull
• Name: transmembrane inner ear; targeted mutation 1.1, Ulrich Mueller
• MGI ID: MGI:5784552
• Synonyms: Tmie^flox
• Gene: Tmie Location: Chr9:110694755-110709141 bp, - strand Genetic Position: Chr9, 60.79 cM
• Alliance: Tmie^tm1.1Mull page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217448
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 5 was floxed. Flp-mediated recombination removed the selection cassette. (J:217448)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmie Mutation: 15 strains or lines available

References

• Original: J:217448 Zhao B, et al., TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells. Neuron. 2014 Dec 3;84(5):954-67
• All: 3 reference(s)