Gata2^tm1.1Dzk
Targeted Allele Detail

Summary

• Symbol: Gata2^tm1.1Dzk
• Name: GATA binding protein 2; targeted mutation 1.1, Elaine Dzierzak
• MGI ID: MGI:5784538
• Synonyms: G2V, Gata2Venus
• Gene: Gata2 Location: Chr6:88170873-88184014 bp, + strand Genetic Position: Chr6, 39.2 cM
• Alliance: Gata2^tm1.1Dzk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232808
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (No functional change, Reporter)
• Mutation: Insertion
• Mutation details: An IRES-Venus reporter gene cassette and a loxP site flanked puromycin resistance gene cassette were targeted to the 3' UTR in exon 6. The puro cassette was excised through cre-mediated recombination. (J:232808)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gata2 Mutation: 29 strains or lines available

References

• Original: J:232808 Kaimakis P, et al., Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors. Blood. 2016 Mar 17;127(11):1426-37
• All: 3 reference(s)