Gt(ROSA)26Sor^tm1Embrp
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1Embrp
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ramesh S Pillai
• MGI ID: MGI:5781116
• Synonyms: Rosa26-pi
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1Embrp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229314
• Parent Cell Line: A9 (ES Cell)
• Strain of Origin: (C57BL/6 x 129P2/OlaHsd)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced into the locus (5' to 3'): a dsRed2 fluorescent protein coding sequence, a lacZ-derived 3' UTR with a loxP-flanked sequence containing perfectly complementary sites for 35 separate MILI-bound piRNAs, and an FRT-flanked Keo (Kanamycin-neomycin) selection marker. (J:229314)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:229314 Yang Z, et al., PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway. Mol Cell. 2016 Jan 7;61(1):138-52
• All: 3 reference(s)