Slitrk3^tm1Jaru
Targeted Allele Detail

Summary

• Symbol: Slitrk3^tm1Jaru
• Name: SLIT and NTRK-like family, member 3; targeted mutation 1, Jun Aruga
• MGI ID: MGI:5781003
• Gene: Slitrk3 Location: Chr3:72954598-72965136 bp, - strand Genetic Position: Chr3, 32.59 cM, cytoband E2
• Alliance: Slitrk3^tm1Jaru page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232385
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced the coding sequence in exon 2. Western blot analysis confirmed the absence of protein expression in the frontal cortex and hippocampus. (J:232385)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slitrk3 Mutation: 48 strains or lines available

References

• Original: J:232385 Takahashi H, et al., Selective control of inhibitory synapse development by Slitrk3-PTPdelta trans-synaptic interaction. Nat Neurosci. 2012 Mar;15(3):389-98, S1-2
• All: 1 reference(s)