Aim2^tm1Jpyt
Targeted Allele Detail

Summary

• Symbol: Aim2^tm1Jpyt
• Name: absent in melanoma 2; targeted mutation 1, Jenny PY Ting
• MGI ID: MGI:5779549
• Gene: Aim2 Location: Chr1:173178445-173293606 bp, + strand Genetic Position: Chr1, 80.33 cM
• Alliance: Aim2^tm1Jpyt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228671
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A floxed neomycin resistance cassette replaced the coding region. (J:228671)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aim2 Mutation: 35 strains or lines available

References

• Original: J:228671 Wilson JE, et al., Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nat Med. 2015 Aug;21(8):906-13
• All: 5 reference(s)