Igsf1^em1Djb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igsf1^em1Djb
• Name: immunoglobulin superfamily, member 1; endonuclease-mediated mutation 1, Daniel J Bernard
• MGI ID: MGI:5779502
• Synonyms: Igsf1^delta312
• Gene: Igsf1 Location: ChrX:48871413-48886626 bp, - strand Genetic Position: ChrX, 26.06 cM
• Alliance: Igsf1^em1Djb page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology removed 312 bp, which includes part of exon 18 and the following intron. This deletion introduces a premature termination codon and is expected to produce a truncated product. (J:240387)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igsf1 Mutation: 10 strains or lines available

References

• Original: J:240387 Turgeon MO, et al., TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice. Endocrinology. 2017 Apr 1;158(4):815-830
• All: 3 reference(s)