Mir142^tm1.1Prdy
Targeted Allele Detail

Summary

• Symbol: Mir142^tm1.1Prdy
• Name: microRNA 142; targeted mutation 1.1, Pavan Reddy
• MGI ID: MGI:5779398
• Gene: Mir142 Location: Chr11:87647690-87647753 bp, + strand Genetic Position: Chr11, 52.21 cM
• Alliance: Mir142^tm1.1Prdy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224541
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The microRNA precursor sequence was replaced with a floxed neomycin resistance casssette. Cre-mediated recombination removed the selection cassette. (J:224541)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir142 Mutation: 7 strains or lines available

References

• Original: J:224541 Sun Y, et al., Mature T cell responses are controlled by microRNA-142. J Clin Invest. 2015 Jul 1;125(7):2825-40
• All: 4 reference(s)