Ehd3^tm1.1Haba
Targeted Allele Detail

Summary

• Symbol: Ehd3^tm1.1Haba
• Name: EH-domain containing 3; targeted mutation 1.1, Hamid Band
• MGI ID: MGI:5776375
• Synonyms: Ehd3^f
• Gene: Ehd3 Location: Chr17:74111836-74139088 bp, + strand Genetic Position: Chr17, 45.2 cM, cytoband E2
• Alliance: Ehd3^tm1.1Haba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231243
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the neo cassette. (J:231243)

Generation of the Ehd3^tm1.1Haba and Ehd3^tm1.2Haba alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ehd3 Mutation: 27 strains or lines available

References

• Original: J:231243 Curran J, et al., Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria. J Biol Chem. 2015 May 8;290(19):12210-21
• All: 4 reference(s)