Syt10^tm1.1Sud
Targeted Allele Detail

Summary

• Symbol: Syt10^tm1.1Sud
• Name: synaptotagmin X; targeted mutation 1.1, Thomas C Sudhof
• MGI ID: MGI:5775545
• Gene: Syt10 Location: Chr15:89666596-89726063 bp, - strand Genetic Position: Chr15, 44.96 cM, cytoband F1
• Alliance: Syt10^tm1.1Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229369
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was created by crossing mice carring Syt10 with a cre transgenic mice to excise the exon 2 of the gene. (J:229369)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Syt10 Mutation: 35 strains or lines available

References

• Original: J:229369 Cao P, et al., Activity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10. Cell. 2011 Apr 15;145(2):300-11
• All: 2 reference(s)