Smad2^{tm6(SMAD2)Rob}
Targeted Allele Detail

Summary

• Symbol: Smad2^{tm6(SMAD2)Rob}
• Name: SMAD family member 2; targeted mutation 6, Elizabeth Robertson
• MGI ID: MGI:5775212
• Synonyms: Smad 2 SF, Smad2SF
• Gene: Smad2 Location: Chr18:76374651-76444034 bp, + strand Genetic Position: Chr18, 51.42 cM
• Alliance: Smad2^{tm6(SMAD2)Rob} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Smad2^{tm6(SMAD2)Rob} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SMAD2 (4087)

  Smad2

  (MGI:108051)

  short form

• Mutation details: A cDNA encoding N-terminally FLAG-tagged human SMAD family member 2 (SMAD2) lacking the alternatively-spliced exon 3 was knocked into the endogenous mouse locus at exon 1, resulting in expression of the short isoform of human SMAD2 in place of the mouse protein. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Smad2 Mutation: 52 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)