Retreg1^tm1.1Cahb
Targeted Allele Detail

Summary

• Symbol: Retreg1^tm1.1Cahb
• Name: reticulophagy regulator 1; targeted mutation 1.1, Christian Hubner
• MGI ID: MGI:5774849
• Gene: Retreg1 Location: Chr15:25843266-25973773 bp, + strand Genetic Position: Chr15, 9.59 cM
• Alliance: Retreg1^tm1.1Cahb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222922
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exons 6 through 8. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. (J:222922)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Retreg1 Mutation: 29 strains or lines available

References

• Original: J:222922 Khaminets A, et al., Regulation of endoplasmic reticulum turnover by selective autophagy. Nature. 2015 Jun 18;522(7556):354-8
• All: 3 reference(s)